A fragment lacking a guanine at nucleotide 208 of the gene replaced the endogenous sequence by homologous recombination. Cre mediated recombination removed a floxed neomycin selection cassette. RT-PCR did not detect transcript using primers designed to amplify sequence downstream of the deleted guanine. (J:103713)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count