A fragment lacking a guanine at nucleotide 208 of the gene replaced the endogenous sequence by homologous recombination. Cre mediated recombination removed a floxed neomycin selection cassette. RT-PCR did not detect transcript using primers designed to amplify sequence downstream of the deleted guanine. (J:103713)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
Intragenic deletion
--
1
3
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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