A targeting vector containing a lacZ-neomycin resistance gene was inserted into exon 1. RNAse protection assay confirmed ablation of the gene. Immunohistochemical analysis detected beta-gal expression in the olfactory bulb, cortex, hippocampus, and dorsal geniculate and ventral posterolateral nuclei of the thalamus. (J:103966)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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