LoxP sites were inserted to flank exons 1 and 2 of the locus. Cre-mediated recombination would result in the deletion of sequence including the initiation ATG, and thereby generate a null allele. (J:103919)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count