LoxP sites were inserted to flank exons 1 and 2 of the locus. Cre-mediated recombination would result in the deletion of sequence including the initiation ATG, and thereby generate a null allele. (J:103919)
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LoxP sites were inserted to flank exons 1 and 2 of the locus. Cre-mediated recombination would result in the deletion of sequence including the initiation ATG, and thereby generate a null allele. (J:103919)