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A floxed PGK-neo selection cassette was inserted in intron 11 and a third loxP element was inserted 900bp upstream of exon 11. Exon 11 encodes the essential channel pore regions M1 and M2. Four silent mutations were introduced into exon 11 as well. (J:104146)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
