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A targeting vector was designed to insert a loxP site upstream and a PGK-neomycin selection cassette flanked by loxP and FRT sites 2 kb downstream of exon 1. The PGK-neo was excised by transient expression of FLP or cre recombinase. The loxP-flanked region encompasses part of the promoter region, the transcription start site, and the first exon. (J:102740)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
