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A cassette containing a splice acceptor, an IRES-EGFP-cre, the pA sequence, and a kanamycin/neomycin resistance gene was inserted into the locus. Cre expression was expected in the presomatic and somatic mesoderm. EGFP activity was not detected in mutant embryos between E9.5-11.5, possibly due to a low level of expression of the EGFP0cre fusion protein mediated by the IRES sequence. (J:102739)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
