A targeting construct was created to flank exons 2 and 3, sequence encoding the homeodomain and Prox domain, with loxP sites. Loss of this sequence would render the locus transcriptionally inactive. (J:102652)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count