EB3 ES cells were targeted with a vector containing the Tet-off regulation cassette for the homeodomain transcription factor Ipf1 and EGFP expression. A floxed neo was removed via cre-mediated excision. EB3 cells carry one allele of Pou5f1 that has been inactivated by targeted integration of E14Tg2a ES cells with an IRESBSDpA selection cassette. (J:102833, J:103479)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count