A targeting vector was designed to insert stop codons in all three reading frames, an IRES-lacZ-pA and a neomycin resistance gene into exon 1. Northern and Western blot analyses confirmed that transcript and protein were absent in mutants. (J:103337)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count