A neomycin resistance gene replaced 107 bp of the first coding exon containing transcription and translation start sites. Northern blot confirmed absence of transcript in mutant mice. Western blot showed absence of protein in mutant liver cell extracts. (J:102333)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEvBrd
Targeted
Insertion, Intragenic deletion
--
1
4
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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