A targeting vector was designed to replace J1 through J4 with a neomycin resistance cassette followed by the 36-65VDJ region with the following amino acid substitutions: A9V, Y32N, I51N, T58I, K59T, S77N, V100E, Y107K, with numbering from the mature amino terminus of the H chain. (J:102308)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Targeted
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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