Log In|Sign Up
EN
A targeting construct was designed to insert a P264L mutation into exon 8. Northern blot demonstrated mRNA levels were comparable in mutants and wild-type mice. Western blot indicated that despite normal mRNA expression, expression of N- and C-terminal fragments was reduced by about 50%. (J:102425)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
