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EN
The endothelial specific receptor tyrosine kinase promoter was used to drive expression of cre recombinase. Nine founder lines were produced and one of these was selected for use that efficiently mediated gene excision. Cre was active in the blood islands of extraembryonic mesoderm at E7.5 and in the dorsal aortae at E8.5. By E11.5 it was active in the endothelial cells of all blood vessels. (J:102190, J:104401)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
