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This transgene overexpresses the rat Agt gene under the control of the adipocyte-specific Fabp4 promoter. Northern blot and RT-PCR analysis indicates specific Agt expression in adipose tissue with small amounts of mRNA detected in muscle and heart and none in liver or kidney. Several lines were made, with this line (Line 1) expressing the lowest levels of Agt. (J:73163)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
