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The targeting event replaced approximately 1 kb of the gene, including the translation initiation site and all but 10 bp of exon 1, with a floxed MC1-neo cassette in reverse orientation. Western blot analysis of lysates of whole E8.5 embryos using affinity-purified antiserum to the C-terminus of human YAP protein produced no signal. (J:102253)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
