A PGK-Neo cassette was inserted into intron 3 and three loxP sites around exons 2 and 3 and the PGK-Neo. Chimeras were mated to Tg(ACTB-cre)13Miya mice to remove exons 2 and 3 and the PGK-Neo cassette. Northern blot analysis and RT-PCR confirmed absence of RNA. (J:102924)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intragenic deletion
--
1
6
23

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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