A cDNA fragment encoding the intracellular portion of the human RET9 isoform was fused in-frame with mouse exon 11 immediately downstream of the transmembrane domain-coding region. The inserted cDNA contained substitutions changing the amino acids M and S at the start of the Ret51 specific sequence to R and I, and was followed by a floxed PGK-neo cassette. (J:102170)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count