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The gene segment from human TCR alpha receptor V24 (TRAV24) to TCR alpha receptor JQ (TRAJ18) was fused with the mouse Tcra-C and placed under the control of the human CD2 enhancer promoter. This construct was injected into C57BL/6 x DBA/2 fertilized eggs. Five founders were identified. Founders 1-4 expressed the transgene at a high frequency whereas founder 5 expressed the transgene at a low frequency. (J:82014)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
