The transgene comprises approximately 20 copies (per haploid genome) of PstI-linearized pUR288, which contains the pBR322 origin of replication, an ampicillin resistance gene and the complete lacZ gene. Presence and copy number of the plasmid was determined by Southern blot analysis. (J:102031, J:102032, J:102033)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count