Log In|Sign Up
EN
Exons 2 and 3 were replaced with the En2A-IRESbetageoPA cassette. The replaced sequence encodes amino acids 194 to 452, encompassing the entire catalytic domain of the protein, including the protein tyrosine phosphatase active-site motif HCXXGXXRS. Western blot failed to detect protein in mutant ES cells. (J:101370)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
