A lacZ/IRES/neo cassette replaced sequences corresponding to bases 418 to 535 of the coding region. RT-PCR analysis detects a gene transcript at high levels in brain, spinal cord, pituitary gland and adrenal gland and at lower levels in eye, thymus, lymph nodes, gallbladder, stomach, small intestine, cecum, colon, testis, epididymis, prostate gland, ovary and white fat; beta-galactosidase expression is not detectable in any tissue. (J:142688)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intragenic deletion
--
1
14
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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