A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are normally detectable in spleen and lymph nodes, spinal cord, eye, lung, pancreas, adrenal gland, stomach, testis, ovary, whole brain, cortex, subcortical region, cerebellum, brainstem, olfactory bulb, Harderian glands, heart, liver, kidney, thymus, bone marrow, skin, gallbladder, urinary bladder, pituitary gland, salivary gland, skeletal muscle, tongue, small intestine, cecum, colon, epididymis, seminal vesicle, coagulating gland, prostate gland, uterus and white fat. Strong lacZ expression was detected in most organs examined. LacZ expression was not detected in gallbladder and uterus.

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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