A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in brain, spinal cord, eye, heart, kidney, pituitary gland, adrenal gland, stomach, large intestine, seminal vesicle, coagulating gland, ovary and uterus; beta-galactosidase expression is detectable in brain, spinal cord, eye, spleen, lymph nodes, esophagus, parathyroid gland, pituitary gland, salivary glands, tongue, male and female reproductive systems.
Basic Information
Disruption caused by insertion of vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count