LoxP sites were inserted to flank exon 11, which encodes amino acids 722-813. These amino acids encompass two transmembrane segments including part of the alpha-2 region essential for exchange activity. (J:101484)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count