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The mouse prion protein promoter was used to drive expression of human microtubule-associated protein tau cDNA with exon 10, but lacking exons 2 and 3. These exons encode four-repeat tau without amino-terminal inserts. Mutant mice expressed the transgene at a level below that of endogenous tau. (J:63887)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
