The mouse ZP3 promoter was used to drive the hairpin construct of RNAi derived from H1foo cDNA in transgenic mice. RT PCR demonstrated a lack of H1foo message in MII oocytes. Immunofluorescence indicated no H1foo protein in the MII oocytes. (J:101326)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count