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Exons 3-5 were replaced with a lacZ reporter. The deleted region encodes the two LIM domains and part of the homeodomain. Expression of the mutant allele was shown in the maxillary and mandibular processes of the first branchial arch, the pinna, and the medial ganglionic eminence of the telencephalon, corresponding to expression of the endogenous locus. (J:101205)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
