The first coding exon was left flanked with loxP sites 2800 bp in front of exon 1 of the gene and and a second loxP site 260 bp after exon 1 in intron 1, upon removal of a floxed neomycin resistance cassette. This allele has some residual endogenous protein expression at either 1.5% or 10% nominal levels. (J:101021, J:108008, J:282335)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count