The first coding exon was left flanked with loxP sites 2800 bp in front of exon 1 of the gene and and a second loxP site 260 bp after exon 1 in intron 1, upon removal of a floxed neomycin resistance cassette. This allele has some residual endogenous protein expression at either 1.5% or 10% nominal levels. (J:101021, J:108008, J:282335)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion
--
1
5
23

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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