The targeting vector consists of a loxP site inserted upstream of exon 2, a second loxP site inserted downstream of exon 2 followed by a FRT-flanked neomycin cassette . Flp mediated recombination removed the neomycin cassette. (J:100949)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count