Cre recombinase cDNA and a PGK-neo were inserted at the ATG to replace the first two coding exons. Immunohistochemical staining demonstrated cre-expressing cells with high density in the cerebral cortex, hippocampus, amgdala and thalamus and with low density in the olfactory system, septal region, basal ganglia, hypothalamus, brainstem and spinal cord. (J:100950)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count