Cre recombinase cDNA and a PGK-neo were inserted at the ATG to replace the first two coding exons. Immunohistochemical staining demonstrated cre-expressing cells with high density in the cerebral cortex, hippocampus, amgdala and thalamus and with low density in the olfactory system, septal region, basal ganglia, hypothalamus, brainstem and spinal cord. (J:100950)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd
Targeted
Insertion
--
1
1
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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