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A targeting construct was designed to introduce a lysine to glutamic acid mutation at amino acid position 641 (K641D) in exon 13. A loxP flanked neomycin resistance gene was included in the targeting vector in intron 13. Position 641 is within the first portion of the slpit kinase domain. (J:100778)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
