A targeting vector was designed to insert loxP sites flanking exon 1, which encodes amino acids 1-98. An FRT-flanked neo cassette was included in the vector and subsequently removed by crossing with mice expressing Flp reocmbinase. (J:100558)
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A targeting vector was designed to insert loxP sites flanking exon 1, which encodes amino acids 1-98. An FRT-flanked neo cassette was included in the vector and subsequently removed by crossing with mice expressing Flp reocmbinase. (J:100558)