A beta-geo cassette was inserted in-frame into exon 1 to create a fusion transcript consisiting of the first third of the Gpx1 coding region and beta-geo. X-gal staining of E13.5 embryos detected expression in the liver, spinal cord, eye and brain stem, and staining of adults demonstrated expression in liver and kidney cortex. (J:62395)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count