A neomycin resistance cassette was inserted and replaced the 5' promoter region, first exon and part of intron 1 of Afmid. The construct also replaced the 5' promoter region, first exon, first intron and a portion of exon 2 of Tk1. Afmid mRNA was not detected in mutant liver, kidney and salivary gland. (J:100247)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count