A neomycin resistance cassette was inserted into exon 1 and introduced a premature translation stop codon into the open reading frame. Successful knock down was confirmed by Northern and Western blot analyses. (J:100272)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count