A nuclear targete cre recombinase sequence replaced the entire coding region of Sox10 in a P1-derived artificial chromosome (PAC ID RP21-529-I6). Several founders were obtained. A representative line was designated line 1. (J:99989)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count