A targeting construct was designed to insert a PGK-neo into exon 1, thereby eliminating 92% of the coding sequence. Western blot confirmed absence of protein in mutant MEFs. (J:99997)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count