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The tumor necrosis factor alpha gene was placed under the control of the mouse alpha cardiac myosin heavy chain promoter. Six founder mice were produced of which, four produced an abnormal phenotype. Only two of the phenotypically abnormal founders reproduce. Lineage 2 contained approximately 5 copies of the transgene. (J:100006)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
