The transgene consists of a 3 kb murine Zfpm1 cDNA under the control of the Gata-1 promoter. A rabbit globin poly(A) addition region and simian virus 40 sequence for polyadenylation signals and transgene detection were also added to the construct. Gata-1 drives the expression of Zfpm1 in the hematopoietic compartment. (J:99745)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count