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A floxed neomycin resistance cassette was inserted into intron 10 and sequence in exon 11 encoding amino-acid residue 393 was mutated from Thr to Ala (ACA to GCA) preventing phosphorylation of this residue. Heterozygotes were crossed with carriers of Meox2tm1(cre)Sor, excising the neomycin resistance cassette and leaving the T393A point mutation. (J:99695)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
