Functional VDJbeta and VJalpha rearrangements were isolated from the beta cell cytotoxic CD8(+) T cell clone NY8.3. Upstream regulatory sequence together with either TCR-beta enhancers or TCR-alpha enhancers, as appropriate, were associated with VDJbeta or VJalpha. (J:44202)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count