An FRP-flanked neomycin resistance cassette downstream of a loxP site was inserted into intron 11 and a second loxP site was inserted in to intron 14 via homologous recombination. Heterozygous mice were bred with Tg(ACTFLPe)9205Dym carriers to excise the neomycin resistance cassette, leaving the loxP sites in introns 11 and 14. (J:99711)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129/Sv
Targeted
Insertion
--
1
--
9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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