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EN
This transgene contains five upstream activating sequence (UAS) elements, a Wnt1 promoter, the rat Smo cDNA containing a W539L mutation, the human placental alkaline phosphatase cDNA under the control of an internal ribosomal entry site, lacZ, and a poly A signal from the murine Wnt1 gene. UAS elements drive the expression of the mutated ligand-independent activated rat Smo gene. Expression of this transgene is dependent on GAL4 expression. (J:73071)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
