The IgH 3' enhancers SH1234 were inserted upstream of the locus. RT-PCR of mutants demonstrated elevated transcript levels in spleenic B-lymphocytes, but normal levels in brain, liver, kidney, lung and thymus. (J:97900)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count