The lacZ gene fused in-frame downstream of the first 45 base pairs of exon 1 was inserted in place of exon 1 along with a floxed neomycin resistance cassette. The neo cassette was excised by breeding with mice bearing Tg(ACTB-cre)13Miya. Beta galactosidase activity was detected immunohistochemically. (J:99731)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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