The lacZ gene was inserted by homologous recombination in place of the first coding exon and proximal portion of the following intron, yielding a fusion protein encoded by the first 7 base pairs of endogenous sequence followed by lacZ. The endogenous protein is not detected by immunohistochemistry, but beta galactosidase activity is observed. (J:99733)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion, Intragenic deletion
--
1
--
22

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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