Cre recombinase is under the control of a 954-bp highly conserved promoter active in all skeletal muscles. Five of eight founder lines induced recombination when crossed to R26R reporter mice. 3 lines (44K, 441G and 453G) showed robust cre activity at E11.5 in skeletal muscle exclusively. The line created here represents line 441G. (J:99340)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count