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The hormone-binding domain (encoding amino acids 281-599) of a modified estrogen receptor was fused in-frame at the 3' end of the coding sequence. Three new amino acids were introduced at the junction. A Floxed Neo cassette was inserted 580 bp down-stream from the polyadenylation site. The polyadenylation signal and other 3' untranslated sequences were left intact. (J:99305)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
