A PGK-neo flanked by loxP sites was inserted into exon B, incorporating an in-frame stop codon upstream from the cassette. Northern blot of RNA from mutant lungs confirmed creation of a null allele.
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count