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A neomycin resistance cassette replaced exons 5-11, which correspond to the first Kunitz domain, the LDL receptor class A domain, the second Kunitz domain, the transmembrane domain and the intracytoplasmic domain. RT-PCR of mutant embryos confirmed absence of transcript. (J:99182)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
